Data Set APSR 2.0 - Concept Differentiation

ID: 2.16.840.1.113883.2.6.60.6.1.1Version Label: Live VersionConcepts: 4 (Groups: 2 - Items: 2)

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Name ID[‑] Datatype[‑] Property[‑] Example[‑] Codes[‑] Description[‑] Source[‑] Rationale[‑] Operationalizations[‑] Comment[‑] Status[‑] Terminology[‑] Value Set[‑] Type[‑] Parent concept[‑] Inherit from[‑]
Differentiation psr-dataelement-55 Differentiation means Grading as classification of tumors according their assumed grade of malignancy. The most often three-tiered grading system is used. Furthermore, the cell type of lympoproliferative neoplasias is classified in that system, too.
Both are coded by the second digit after the slash in the M chapter (Morphology axis) of ICD-O-3

It also means differentiation according the lymphocyte type in malignant lymphomas.
http://www.who.int/classifications/icd/adaptations/oncology/en/  All grading systems share the assumption that a tumor is as more malignant as it differs morphologically from the original tissue. Highly differentiated tumors (very similar to the original tissue) are low malignant (low grade, grade 1), poorly differentiated tumors are highly malignant ones (high grade, grade 3 or 4).
    draft
    Histological grade finding (finding) (SNOMED Clinical Terms: 373372005)
      Group
      Grading/Immunophenotype psr-dataelement-104 Code
      • 1
      • 2
      • 3
      • 4
      • 5
      • 6
      • 7
      • 8
      • 9
      • Asked but unknown
      Differentiation of a malignant tumor, both as grading in a 4-tiered grading system (WHO-grading) and as immunophenotype for malignant lymphomas and some leukemias http://www.who.int/classifications/icd/adaptations/oncology/en/
        draft
        Grade Cancer (Logical Observation Identifier Names and Codes: 21858-6)
          ICD-O-3 Differentiation 2015-11-13T19:07:32 (dynamic)
          Item Differentiation
          Assessment Scales (Score) psr-dataelement-99 Code
          • Scoring systems
          Assessment scales or scores are a special, highly structured form of clinical findings (see scoring systems)
            draft
            Assessment scales (assessment scale) (SNOMED Clinical Terms: 273249006)
              Item Differentiation