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Thrombocytopenia, anasarca, fever, renal insufficiency, organomegaly syndrome (disorder)
TAFRO syndrome
TAFRO (thrombocytopenia, anasarca, fever, renal insufficiency, organomegaly) syndrome
Thrombocytopenia, anasarca, fever, renal insufficiency, organomegaly syndrome
A rare systemic disease characterized by acute or subacute onset of thrombocytopenia, anasarca (edema, pleural effusion, ascites) and systemic inflammation (fever and/or elevated C-reactive protein). Minor diagnostic categories are Castleman disease-like features on lymph node biopsy, reticulin myelofibrosis and/or increased number of megakaryocytes in bone marrow, progressive renal insufficiency and mild organomegaly including hepatosplenomegaly and lymphadenopathy. Most patients show elevated levels of serum alkaline phosphatase while marked polyclonal hypergammopathy is rare.
syndroom van trombocytopenie, anasarca, koorts, nierinsufficiƫntie en organomegalie
syndroom van trombopenie, gegeneraliseerd oedeem, febris, nierschade en visceromegalie
TAFRO-syndroom
syndroom van trombopenie, gegeneraliseerd oedeem, pyrexie, nierschade en splanchnomegalie
Id1187615007
StatusPrimitive
Associated morphologyAnasarca
Associated morphologyInflammatory morphology
Has interpretationAbnormal
InterpretsHemostatic function
Has interpretationBelow reference range
InterpretsPlatelet count
Has interpretationAbove reference range
InterpretsBody temperature
ICD-10 complex map reference set
TargetM35.8
RuleTRUE
AdviceALWAYS M35.8 | POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
CorrelationSNOMED CT source code to target map code correlation not specified