Cerebral degeneration	Congenital neurological disorder	Developmental hereditary disorder	Hereditary degenerative disease of central nervous system	Hereditary disorder of musculoskeletal system	Leukoencephalopathy	Metaphyseal chondrodysplasia	X-linked recessive hereditary disease
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Leukoencephalopathy with metaphyseal chondrodysplasia syndrome (disorder)
	Leukoencephalopathy with metaphyseal chondrodysplasia syndrome
	The association of leukoencephalopathy and metaphyseal chondrodysplasia has been reported in four men from a three-generation family. Onset manifests by spastic paraplegia at the age of 2, followed by tremor, ataxia, optic atrophy, and spastic tetraparesis. Transmission is X-linked and the gene responsible of the disease may be located at Xq25-q27.
	syndroom van leukencefalopathie met metafysaire dyschondroplasie
	leuko-encefalopathie-metafysaire chondrodysplasie-syndroom leukencefalopathie-metafysaire dyschondroplasie-syndroom

Id	719405005
Status	Primitive

Associated morphology	Degenerative abnormality
Finding site	Cerebral white matter structure

Associated morphology	Dysplasia
Finding site	Bone structure
Occurrence	Congenital
Pathological process	Pathological developmental process

Interprets

Height / growth measure

DHD Diagnosis thesaurus reference set

ICD-10 complex map reference set

Target	G11.4
Rule	TRUE
Advice	ALWAYS G11.4 \| POSSIBLE REQUIREMENT FOR ADDITIONAL CODE TO FULLY DESCRIBE DISEASE OR CONDITION
Correlation	SNOMED CT source code to target map code correlation not specified