Autosomal recessive hereditary disorder	Combined immunodeficiency disease
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Susceptibility to respiratory infection associated with CD8alpha chain mutation (disorder)
	Susceptibility to respiratory infection associated with CD8alpha chain mutation
	Familial CD8 deficiency
	A rare primary immunodeficiency due to a defect in adaptive immunity characterized by the absence of CD8 positive T cells with normal immunoglobulin and specific antibody titers in blood and susceptibility to recurrent respiratory bacterial and viral infections. Symptom severity ranges from fatal respiratory insufficiency to mild or asymptomatic phenotypes.
	vatbaarheid voor luchtweginfectie door mutatie in CD8-alfaketen
	familiaire CD8-deficiëntie gevoeligheid voor luchtweginfectie door mutatie in CD8-alfaketen familiale CD8-deficiëntie

Id	766983005
Status	Primitive

Pathological process

Abnormal immune process

DHD Diagnosis thesaurus reference set

ICD-10 complex map reference set

Target	D84.8
Rule	TRUE
Advice	ALWAYS D84.8
Correlation	SNOMED CT source code to target map code correlation not specified

Target	Q99.9
Rule	TRUE
Advice	ALWAYS Q99.9
Correlation	SNOMED CT source code to target map code correlation not specified